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ACC Clinical Trials
see Mitotane Section
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Coalition of Cancer Cooperative Groups
Italian Protocol -
FIRM-ACT Italian Protocol
A Study to Determine Safety, Pharmacokinetics and Pharmacodynamics of
Intravenous TKM 080301
in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients
Molecular Profiling
- or SCRI-CA-001 Study (Formerly known as the Bisgrove Trial).
Joyce Ingold RN MSN OCN
TGen Clinical Research Services
Patient Care Coordinator
Office Phone: 480-323-1339
jingold@shc.org
About Mitotane
Genera
l Mitotane Info
Adjuvant Mitotane
Treatment for Adrenocortical Carcinoma
New England Journal of Medicine
Optimal treatment
of adrenocortical carcinoma with mitotane
Recurrence
of adrenal cortical carcinoma following resection: surgery alone can achieve results equal to surgery plus mitotane
Mitotane Absorption
- Chocolate, Emulsion, and Milk
Low-Dose -
Monitored Mitotane Treatment Achieves the Therapeutic Range with Manageable
Side Effects in Patients with Adrenocortical Cancer
Cholesterol -
Mitotane and Cholesterol
More ACC Chemo Articles
Overview -
Systemic chemotherapy for adrenocortical carcinoma: comparative responses to conventional first-line therapies.
Italian Protocol -
Etoposide, doxorubicin and cisplatin plus mitotane in the treatment of advanced
adrenocortical carcinoma: a large prospective phase II trial
Combination chemotherapy
in advanced adrenocortical carcinoma
Mitotane -
New England Journal of Medicine: Adjuvant Mitotane Treatment for Adrenocortical Carcinoma
Sutent -
Metastatic adrenocortical carcinoma treated with sunitinib: a case report.
Sutent
- Sunitinib Inhibits Cell Proliferation and Alters Steroidogenesis by Down-Regulation of HSD3B2 in Adrenocortical Carcinoma Cell
s
Streptozocin
and o,p'DDD in the treatment of adrenocortical cancer patients: Long-term survival in its adjuvant use
Platinum -
Expression of excision repair cross complementing group 1 and prognosis in adrenocortical carcinoma patients treated with platinum-based chemotherapy.
Cisplatin Neuropathy Prevention -
Cisplatin-induced peripheral neuropathy: Neuroprotection by erythropoietin without affecting tumour growth
Thalidomide -
CASE 2. Response in a Patient With Metastatic Adrenal Cortical Carcinoma With Thalidomide
EGFR -
Mutational analysis of the BRAF, RAS and EGFR genes in human adrenocortical carcinomas.
IGF -
Preclinical Targeting of the Type 1 Insulin-like Growth Factor Receptor in Adrenocortical Carcinoma.
IGF -
Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors.
IGF -
Rosiglitazone Inhibits Adrenocortical Cancer Cell Proliferation by Interfering with the IGF-IR Intracellular Signaling.
IGF -
Preclinical Targeting of the Type 1 Insulin-like Growth Factor Receptor in Adrenocortical Carcinoma.
Treatment of advanced adrenocortical carcinoma with
erlotinib plus gemcitabine
Gemcitabine plus metronomic 5-fluorouracil
or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter phase II study.
Mebendazole
inhibits growth of human adrenocortical carcinoma cell lines implanted in nude mice
Oral
gossypol
in the treatment of metastatic adrenal cancer
Nexava -
Sustained remission with the kinase inhibitor sorafenib in stage IV metastatic adrenocortical carcinoma
Avastin -
Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma.
Resorcylic acid lactone L-783,277 inhibits the growth of the human adrenal cancer cell line H295R in vitro
Molecular Profiling for Targetted Therapies
ABC News Fighting Disease with DNA
Targeted Therapies Overview
Predictive markers help oncologists match patients with the most effective treatments.
Gene-expression profiling of adrenocortical carcinoma.
Molecular Profiling
- or SCRI-CA-001 Study (Formerly known as the Bisgrove Trial).
Joyce Ingold RN MSN OCN
TGen Clinical Research Services
Patient Care Coordinator
Office Phone: 480-323-1339
jingold@shc.org
ATAC ACC Tumor Analysis & Tissue Bank
- Free for Eligible Patients
Molecular Profiling Institute
Rational Therapeutics Chemo-Sensitivity Testing
Genomic and expression profiling of adrenocortical carcinoma: application to diagnosis, prognosis and treatment.
- Full Text $60
Analysis by cDNA microarrays of gene expression patterns of human adrenocortical tumors.
Gene Expression Profiling of Human Adrenocortical Tumors Using Complementary Deoxyribonucleic
Acid Microarrays Identifies Several Candidate Genes as Markers of Malignancy
Review: Side Effects of Approved Molecular Targeted Therapies in Solid Cancers
Application of ATP based bioluminescence tumor chemosensitivity assay in the chemotherapy of pediatric solid tumor
Genetics
Highly prevalent TP53 mutation predisposing to many cancers in the Brazilian population: a case for newborn screening?
p53 tetramerization domain mutations: germline R342X and R342P, and somatic R337G identified in pediatric patients with Li-Fraumeni syndrome and a child with adrenocortical carcinoma.